Immunolocalization of cathepsin D in normal and neoplastic human tissues.
نویسندگان
چکیده
منابع مشابه
Immunolocalization of cathepsin D in normal and neoplastic human tissues.
The aspartic proteinase cathepsin D was purified from human spleen and localised in various formalin fixed paraffin embedded human tissues using the peroxidase-antiperoxidase (PAP) technique. Cathepsin D was shown not only in macrophages but also in other connective tissue cells, and in epithelium. It was present in spleen (littoral cells and cells within Malpighian bodies), liver (hepatocytes ...
متن کاملEnzymes of uracil catabolism in normal and neoplastic human tissues.
Enzymes of the pyrimidine base catabolism, dihydrouracil dehydrogenase (EC 1.3.1.2), dihydropyrimidinase (EC 3.5.2.2), and beta-ureidopropionase (EC 3.5.1.6) were compared in the cytosolic extract of several normal and neoplastic human tissues. The activity was measured by following the catabolism of [6-14C]-uracil to dihydrouracil, carbamyl-beta-alanine, and beta-alanine. Substrate inhibition,...
متن کاملHuman Secretoglobins in Normal and Neoplastic Cells and Tissues
Secretoglobins is a newly described polypeptide family that has gained a lot of interest in human cancer and inflammation research. Although the first secretoglobin polypeptide was discovered more than 30 years ago, their physiological function is still not known. The aim of this thesis was to study the expression of secretoglobins in normal and neoplastic human cells and tissues, and to clarif...
متن کاملHuman histocompatibility antigens in normal and neoplastic tissues.
More than 20 different leukocyte or tissue antigens can presently be recognized; they belong to one complex system (HL-A) which is, from the genetic point of view, very similar to the H-2 system in the mouse. Another independent system consisting of two antigens has also been well defined, the Group Five system. The methods of defining these antigens, their tissue distri bution, and complex rel...
متن کاملCytotoxic effects of D-glucosamine on the ultrastructures of normal and neoplastic tissues in vivo.
The effects of D-glucosamine on the fine structures of Walker carcinoma and of the liver and kidney in rats were studied in vivo. Continuous administration of D-glucosamine for 18 hr resulted in a slight dilation of the cisternae of the endoplasmic reticulum and Golgi sacs of the tumor cells and liver parenchymal cells. The epithelial cells of the renal tubules contained lamellar structures wit...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1986
ISSN: 0021-9746
DOI: 10.1136/jcp.39.12.1323